Drifting vertical current meter, moored aanderaa thermistor chain, and XBT data : Jasin 1978 Atlantis-II cruise (102)

The report presents summaries of three data sets taken at and in the vicinity of the oceanographic moorings deployed in the 1978 Joint Air-Sea Inte raction Project (JASIN). The data sets are: (1) the temperature, pressure and vertical motion records from the freely drifting Vertical Current Meters (VCMs) deployed from the ATLANTIS II, (2) the temperature data from the Aanderaa thermistor chains on W.H.O.I. mooring 653, designated as JASIN mooring W3, and (3) the expendable bathythermograph (XBT) data collected from the ATLANTIS II while participating in the JASIN Project.Prepared for the Office of Naval Research under Contract N00014-76-C-0197; NR 083- 400 and for the National Science Foundation under Grant OCE 77-25803

Measuring Cortisol in the Classroom with School-Aged Children—A Systematic Review and Recommendations

The collection of salivary cortisol has been chosen as one of the least intrusive, easiest to collect, analyze, and store methods of obtaining information on physiological changes. It is, however, not clear what the best practice is when collecting salivary cortisol from children within the school setting. The aim of this systematic review is to evaluate the feasibility of cortisol collection in schools for future research and to make recommendations for best practice. The review included 25 peer-reviewed articles from seven databases. The hypotheses of the included studies vary, but they all use cortisol as a diurnal, baseline, or acute measure, or to measure the effect of an intervention. Two methods of salivary cortisol collection were preferred by most of the research, i.e., passive drool or cotton Salivettes. The review has concluded that cortisol is a physiological marker that can be successfully measured in school-based research. However, there are discrepancies across studies when evaluating the collection guidelines, protocols, and instructions to participants as well as transparency of the success rate of obtaining all samples. Recommendations are made for future research to address and avoid such discrepancies and improve cross-study comparisons by implementing standard protocol guidelines

Opinion Paragraph Writing Intervention for Students with Significant Disability

Increasingly, technology has been used to provide access to academic curricula for students with moderate to severe intellectual disability. In the current pilot study, we used a multiple probe across participants design to evaluate the effectiveness of a technology-based instructional package on the opinion writing skills of three middle school students with moderate and severe intellectual disability. Findings suggest that the intervention resulted in improved performance across all three participants and that all participants maintained performance at levels greater than baseline. Limitations and implications for practice and future research are discussed

Atlantis II : cruise 102 : preliminary CTD data from Jasin 1978

102 profiles of conductivity, temperature, and depth (pressure) (CTD) were taken in the JASIN area northwest of Scotland in July-September 1978. These stations consisted of single and yo-yo profiles. The data set includes 14 stations taken near Anton Dohrn Seamount at 57°30'N, 11°W . Plotted profiles of temperature, salinity, sigma-theta, and buoyancy frequency, and a listing of the data, are included for most stations.Prepared for the Office of Naval Research under Contract N00014-76-G-0197, NR 083-400, and for the National Science Foundation under Grant OCE77-25803

An Exploration of Novice Programmers' Comprehension of Conditionals in Imperative and Functional Programming

2Students of introductory programming courses are expected to develop higher-order thinking skills to inspect, understand and modify code. However, although novices can correctly write small programs, they appear to lack a more abstract, comprehensive grasp of basic constructs, such as conceiving the overall effect of alternative conditional flows. This work takes a little-explored perspective on the comprehension of tiny programs by asking students to reason about reversing conditionals in either an imperative or a functional context. More specifically, besides deciding if the given constructs can be reversed, students had to justify their choice by writing a reversing program or by providing suitable counterexamples. The students’ answers to four reversibility questions have been analysed through the lens of the SOLO taxonomy. 45% of students correctly identified the reversibility for the four code items; furthermore, more than 50% of each cohort were able to provide correct justifications for at least three of their four answers. Most incorrect answers were due to failures to consider border cases or to edit the conditional expressions appropriately to reverse the construct. Differences in comprehension between functional and imperative languages are explored indicating the explicit else paths of the functional examples facilitate comprehension compared with the implicit else (no update) of its imperative counterpart.partially_openopenMirolo, Claudio; Izu, CruzMirolo, Claudio; Izu, Cru

Psychological dimensions of retirement.

The chapters that follow examine the character of, and issues relating to, western retirement experiences. As our populations age, issues relating to the nature of retirement are of growing importance. Population ageing is a global issue. For instance, Jacobsen, Kent, Lee, & Mather (2011) report that currently one-fifth of the Japanese population is aged over 65 and estimated to increase to one-third of the population by 2040. Based on Bogomolny’s (2004) calculations, by 2025, there will 2 workers in Japan for every person over 65. By 2030 to 2040, 20% of the United States population (i.e., 70 million people), will be aged over 65 (Conrad Glass & Flynn, 2000; Jacobsen, Kent, Lee & Mather, 2011). A drop in the number of workers per government funded beneficiaries from 3.3. to 2.2 has also been predicted (Social Security Board of Trustees, 2008). Many European countries will have similarly high proportions of their population aged over 65 (Heyma, 2004) with concomitant dependency ratios, as will Australia and New Zealand (Kippen, 2002; Statistics New Zealand, 2012). In the 1970s and 1980s there was a trend toward early retirement, however this began to be reversed in many countries in the 1990s. Participation rates in most OECD countries for older workers (50-64 years) have increased to an average of 63% in 2008. Some countries have seen considerable increases in participation rates for these workers (e.g. New Zealand, Netherlands) and in even older workers (65-69 years) (OECD, 2011). Along with the increasing expansion of working lives has come an evolution of the pathways to retirement. Retirement is no longer necessarily a “clean break” from the workforce, with many researchers arguing that the transition from work to retirement is now “blurred”. Retirement is not a single discrete event but can be viewed as an individual process, where for many paid employment still plays a significant role well into the “third age”. The changing nature of retirement over the past few decades highlights the need to continually reassess how we conceptualise it in the literature and how it impacts on the individual, organisations and society. This book seeks to address some of the psychological dimensions of retirement prominent in the literature. The initial chapter of this book outlines a number of definitions pertinent to the topic of retirement. This is followed by an examination of issues that affect retirement decisions. Next, psychological wellbeing and physical health issues are examined in relation to retirement. The final chapters examine the interplay between work and retirement, the role of leisure in retirement, the experiences of women, and the sources and role of social support in retirement

The object of regulation: tending the tensions of food safety

“I’m struggling to see what it actually is,” says Alison, peering into a colander of defrosting meat. What “it” is, we propose in this paper, is helpfully thought of as “the object of regulation” in at least three senses, which together signal both our inheritance of a Foucauldian problematic and our departure from it. Our suggestion is that much of even the best work on biopolitics, biopower, and biosecurity that has been inspired and informed by these writings has replicated Foucault’s own struggle to get to grips with the complexity of matters that he variously refers to “natural” or “artificial” “givens”. By following science and technology studies (STS) scholars in using broadly ethnographic techniques to explore objects as and at the intersection of practices, we redress this balance somewhat by thinking through an empirical study of the securing of food safety, specifically Alison’s inspection of a restaurant kitchen. What we find is that the securing of meat as a material object of regulation is primarily done by involving multiple versions of the future, something which requires a great deal of usually under-recognised, under-valued, and under-theorised articulation work. With risk based regulation, cost sharing, and public sector cuts in the UK set to redefine the ways in which Alison and her colleagues engage with food business operators, we conclude by arguing for a greater appreciation of the skilful work of tending the tensions of food safety, as well as recognition of its limitation

Fostering Program Comprehension in Novice Programmers - Learning Activities and Learning Trajectories

This working group asserts that Program Comprehension (ProgComp) plays a critical part in the process of writing programs. For example, this paper is written from a basic draft that was edited and revised until it clearly presented our idea. Similarly, a program is written incrementally, with each step tested, debugged and extended until the program achieves its goal. Novice programmers should develop program comprehension skills as they learn to code so that they are able both to read and reason about code created by others, and to reflect on their code when writing, debugging or extending it. To foster such competencies our group identified two main goals: (g1) to collect and define learning activities that explicitly address key components of program comprehension and (g2) to define tentative theoretical learning trajectories that will guide teachers as they select and sequence those learning activities in their CS0/CS1/CS2 or K-12 courses. The WG has completed the first goal and laid down a strong foundation towards the second goal as presented in this report. After a thorough literature review, a detailed description of the Block Model is provided, as this model has been used with a dual purpose, to classify and present an extensive list of ProgComp tasks, and to describe a possible learning trajectory for a complex task, covering different cells of the Block Model matrix. The latter is intended to help instructors to decompose complex tasks and identify which aspects of ProgComp are being fostered

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatment of immune-mediated diseases. To this end, we designed a screen for novel Treg-inducing compounds based on our understanding of the mechanisms of Treg induction by the well-characterized immunosuppressive AhR ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). We screened a ChemBridge small molecule library and identified 10-chloro-7H-benzimidazo[2,1-a]benzo[de]​Iso-quinolin-7-one(10-Cl-BBQ) as a potent AhR ligand that was rapidly metabolized and not cytotoxic to proliferating T cells. Like TCDD,10-Cl-BBQ altered donor CD4+ T cell differentiation during the early stages of a graft versus host (GVH) response resulting in expression of high levels of CD25, CTLA-4 and ICOS, as well as several genes associated with Treg function. The Treg phenotype required AhR expression in the donor CD4+ T cells. Foxp3 was not expressed in the AhR-induced Tregs implicating AhR as an independent transcription factor for Treg induction. Structure-activity studies showed that unsubstituted BBQ as well as 4, 11-dichloro-BBQ were capable of inducing AhR-Tregs. Other substitutions reduced activation of AhR. Daily treatment with 10-Cl-BBQ during the GVH response prevented development of GVH disease in an AhR-dependent manner with no overt toxicity. Together, our data provide strong support for development of select BBQs that activate the AhR to induce Tregs for treatment of immune-mediated diseases

Verbal short-term memory deficits in Down syndrome: phonological, semantic, or both?

The current study examined the phonological and semantic contributions to the verbal short-term memory (VSTM) deficit in Down syndrome (DS) by experimentally manipulating the phonological and semantic demands of VSTM tasks. The performance of 18 individuals with DS (ages 11–25) and 18 typically developing children (ages 3–10) matched pairwise on receptive vocabulary and gender was compared on four VSTM tasks, two tapping phonological VSTM (phonological similarity, nonword discrimination) and two tapping semantic VSTM (semantic category, semantic proactive interference). Group by condition interactions were found on the two phonological VSTM tasks (suggesting less sensitivity to the phonological qualities of words in DS), but not on the two semantic VSTM tasks. These findings suggest that a phonological weakness contributes to the VSTM deficit in DS. These results are discussed in relation to the DS neuropsychological and neuroanatomical phenotype